ABSTRACT
Background: The outcomes following COVID positive donor utilization for heart transplant are unknown. Method(s): UNOS database was analyzed for heart transplants performed after the declaration of COVID pandemic on 11th March 2020 until 31st December 2021. The cohort was divided into two groups based on donor COVID antigen and NAAT results. Result(s): Since the onset of pandemic, there were 6855 heart transplants reported. COVID antigen or NAAT results were available in 5529 donors at the time of donation, of which 38 (0.7%) were positive. COVID positive donors (CPD) were accepted for older recipients (age 54 vs 48, p=0.04). Listing status 1 and 2 were similar in both groups (9% vs 5% and 24% vs 23% respectively). Durable mechanical support (LVAD, RVAD, TAH) were similar in both groups pre-transplant (31% vs 33%, p=0.3). There was no difference in days on waitlist (183 vs 176 days, p=0.9). Both groups had similar travel distance (261 vs 239 nautical miles, p=0.4) and ischemic time (3.6 vs 3.5 hours, p= 0.8). Simultaneous renal transplant rates were similar (10% vs 9%, p=0.8). CPD utilization increased with time (figure 1A) and was uniform across most UNOS regions (figure 1B) Post-transplant, there was no difference in length of stay (24 days in both groups) and acute rejection episode prior to discharge (4% vs 8%, p=0.6) or within one year (3% vs 4%). There were no deaths reported in the CPD group during a mean 72 days of follow up (range 0-365 days) (figure 2). Known hospitalization for rejection management were similar (3% vs 4%) post-transplant. Conclusion(s): Active COVID infection in donors did not affect survival or rejection rates in the short-term post-heart transplantCopyright © 2022
ABSTRACT
COVID-19 (Corona) virus has spread across the world threatening lives of millions of people. In India first COVID-19 case was detected on 30th January 2020 in Kerala. To minimize the spread of Corona Virus, countries all over the world implemented complete lockdown. Due to complete lockdown even people who are not exposed to corona virus, have to self-quarantine to keep themselves safe from getting infected by the disease. People (especially Indians) have never experienced such complete lockdown and quarantining situations before. Thus, this creates a space for curiosity that how people are going to react to this situation. The present study aims to analyse how self-quarantined people during COVID-19 lockdown period are reacting to quarantining, what measures they are taking to deal with this situation, and what are their sentiments towards quarantining. The study also aims to measure their Happiness and to identify the factors that are statistically significant to Happiness. For this study, the data is collected through a survey method. Multiple correspondence analysis are performed to analyse the survey data. The happiness score is evaluated by using the GNH (Gross National Happiness) methodology. Proportional Odd Logistics Regression is used to identify factors that are statistically significant in predicting happiness. The study suggests that family factor is related to the happiness of the self-quarantined people during such lockdown situations. © 2022,International Journal of Advanced Computer Science and Applications. All Rights Reserved.
ABSTRACT
The present review describes about the disease and the fungal agent in brief, and also stresses for establishment of mechanically ventilated hospital wards across the country. Second wave of COVID-19 pandemic in India has been complicated by high infection rate (R-0), 600% jump in medical oxygen demand by COVID hospitals, and after all emergence of Mucormycosis since April-May 2021 leading to fatal complications. Mucormycosis is a very rare infection in humans. It is caused by exposure to mucor mould/ fungi which is commonly found in soil, plants, manure, and decaying fruits and vegetables. These Fungi belonging to the class Zygomycetes and order Mucorales often cause devastating angio-invasive infections, primarily in co-morbid and immunocompromised patients. The emergence of mucormycosis is being reported globally. In India, people with diabetes mellitus are highly susceptible to the disease. But during the second wave of Covid-19 in India, several cases of mucormycosis, also called the "black fungus" disease, have been reported among convalescing and convalescent COVID-19 patients across India with a mortality rate of 50%. More than 5000 cases of mucormycosis during the second wave of Covid-19, have been reported in about 21 states of the country, with Maharashtra and Gujarat states reporting highest number of cases (as on 21 May 2021). The infection has claimed over 120 lives so far, and has complicated recovery from Covid-19 in many more. The Indian Union health ministry has declared mucormycosis as a notified disease under the Epidemic Diseases Act, 1897.